Metabolomics, Genomics and Proteomics

Pharmacogenomics

Pharmacogenomics

The study of the role of the genome in medication response is known as pharmacogenomics. The combination of pharmacology and genetics is reflected in the term (pharmaco- + genomics). Pharmacogenomics studies how a person's genetic composition influences their pharmacological reaction. It examines the impact of acquired and inherited genetic variation on drug response in patients by linking gene expression or single-nucleotide polymorphisms to pharmacokinetics (drug absorption, distribution, metabolism, and elimination) and pharmacodynamics (effects mediated by a drug's biological targets). The terms pharmacogenomics and pharmacogenetics are frequently used interchangeably. Although both names refer to medication response influenced by genetic factors, pharmacogenetics focuses on single drug-gene interactions, whereas pharmacogenomics takes a more genome-wide approach, including genomics and epigenetics while addressing the impact of numerous genes on drug response.