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Ya-Ju Hsieh


Ya-Ju Hsieh

Molecular medicine Research center,Taiwan

Biography

Ya-Ju Hsieh has her expertise in mass spectrometry of metabolomics and proteomics analysis. Her study is major in using quantitative metabolomics profiling approaches to investigate urine samples of cardio surgery patients with or without cardioplegia treatment. The platform was developed by Prof. Liang Li from University of Alberta, Canada, which is based on modified metabolites with dansyl group which can efficiently improve the ionization efficiency of metabolites for 1~3 orders. Using this method, we detected
more than 14,000 metabolites from 100 samples which provides systemic analysis of metabolomicsalteration. This method was focused on metabolites with amine and phenol  functional groups, and the platform to label alcohol, aldehyde and acid are still working on.

Abstract

Abstract : Bretschneider solution induced urine metabolomics alteration in cardiac surgery patients