Metabolomics & Systems Biology

Biography

Alan Prem Kumar earned his PhD from University of North Texas, USA. From his PhD work, he discovered a novel regulatory protein, PyrR for pyrimidine biosynthetic pathway in Pseudomonas, Because pyrimidine biosynthesis is an essential step in the progression of secondary Pseudomonas infection, PyrR presents an attractive anti-Pseudomonal drug target. Dr. Kumar then pursued Postdoctoral training in Cancer Research at Sidney Kimmel Cancer Center, California, USA. He was awarded a postdoctoral Fellowship for his work on the role of nuclear receptors in the transcriptional regulation of human myeloperoxidase, a leukocyte enzyme implicated as causative agent in atherosclerosis and Alzheimer’s disease. Dr. Kumar relocated back to Singapore to join the Faculty of Medicine, National University of Singapore as an independent Principal Investigator to continue on his expertise on nuclear receptor amd cancer biology. His current research interest includes the role of nuclear receptors involved in the regulation of target genes and elucidate mechanism and association signal pathways. Another area of interest is aimed at developing new derivative drugs with hopefully fewer side effects.

Research Interest

Metabolomics